Trellis Vitality offers a GLP-1 program built around clinician oversight, lab monitoring and body composition, with a clearly published price table. A one-month plan is $150 for semaglutide or $199 for tirzepatide. Longer plans lower the displayed monthly rate, but they deserve a separate look at billing and cancellation before you commit 1.
Its appeal is the combination of straightforward medication pricing and a stated focus on strength, nutrition and monitoring. The limitation is that a well-described program is not evidence that its particular formulations preserve muscle or deliver better results than another provider. Evaluate the care you will actually receive and the complete cost, rather than treating the body-composition message as a proven clinical advantage.
Prices: monthly plans versus longer terms
Trellis publishes three program lengths. Semaglutide is $150 per month for one month, $140 per month for three months and $133 per month for six months. Tirzepatide is $199, $189 and $179 per month across the same lengths. The program page says the price is the same across doses 1.
At the displayed rates, three months total $420 for semaglutide or $567 for tirzepatide, while six months total $798 or $1,074. These are the monthly-rate calculations, not confirmation that the entire amount is charged upfront. The public table does not, by itself, settle renewal terms, when installments are collected, or what happens if treatment ends early.
The one-month price is the most useful starting point if flexibility matters. Longer terms can reduce the monthly figure, but ask whether the reduction requires prepayment or a contract and whether unused treatment can be refunded. Also confirm that labs, follow-up, shipping and injection supplies are covered by the quoted plan rather than assuming every item described on the page is included in every tier.
What the program promises to provide
Trellis describes a free clinical assessment, a Vitality Lab Kit to establish a baseline, ongoing review and a 90-day retest. The program emphasizes protein intake, resistance training, hydration and tracking fat and lean mass instead of watching scale weight alone 1.
That approach may be useful if you want a structured discussion about nutrition and strength during treatment. Before joining, find out how body composition is measured, which tests are included, who explains the results and how often you can speak with the care team. “Monitoring” is most valuable when it leads to clear advice you can follow, not simply another dashboard number.
The page also discusses glycine-containing formulations, microdose options and complementary protocols. These require their own clinical assessment. Their presence in a program does not establish that an added ingredient prevents muscle loss, or that another peptide is necessary for a successful weight-management plan.
Medication sourcing and approval status
The current program page identifies Vials Rx as the compounding pharmacy. Trellis describes batch checks for potency, sterility, pH and endotoxins. Those are company descriptions of its sourcing and testing arrangements, not an independent inspection performed by this publication 1.
Trellis also explicitly states that compounded medications are not FDA-approved finished products and should not be described as equivalent to branded medicines. That distinction matters when comparing the program with a prescription for an FDA-approved product. Ask which pharmacy will prepare your prescription, what formulation is prescribed and how to contact the pharmacy about storage or labeling questions.
Enrollment, delivery and ongoing care
You begin with a health assessment. A clinician reviews your medical history and any available lab information, then decides whether medication is appropriate. A prescription is not guaranteed. People switching from another compounded program can bring recent labs for review, according to Trellis 1.
The pharmacy section describes preparing and shipping orders within 24–48 hours after order intake, using cold packing and UPS. This is not the same as receiving medication within 48 hours of starting an assessment: clinical review, prescribing, pharmacy intake and carrier delivery are separate stages. Ask when your first payment is collected and when the company expects your prescription to reach the pharmacy.
State availability needs confirmation
A banner advertises clinicians in all 50 states, but the program FAQ is more specific: the GLP-1 program is not offered everywhere and currently excludes Connecticut, Ohio and South Carolina at minimum 1. The narrower program-specific statement is the one to use for planning.
If you live in one of those states, do not rely on the banner. Elsewhere, confirm availability during assessment before paying or moving your existing care. Our state coverage guide explains why provider reach and medication shipping rules can differ.
Who should consider Trellis?
Trellis may suit someone who wants published one-month GLP-1 prices and a care discussion that includes nutrition, labs and maintaining strength. It is less suitable if you need service in an excluded state, want insurance billing, or expect a guarantee that a specific formulation will preserve muscle. The company says the program is generally cash-pay and advertises HSA/FSA eligibility, which still depends on your own plan 1.
Our verdict: a useful program to compare on cost and care structure, with state restrictions and longer-term billing to clarify. Start with the one-month rate, confirm the complete package, and compare it with our GLP-1 telehealth board before committing.