Direct Meds review
Direct Meds is a Utah-based telehealth provider offering compounded semaglutide and tirzepatide in injection and sublingual formats.
Direct Meds publishes its price before the medical intake — you can see what it costs without handing over your health history first.
On this page
- Semaglutide
- From $249/mo (compounded oral)
- Tirzepatide
- From $299/mo (compounded oral)
- Coverage
- All US states except Mississippi and Louisiana, per its own FAQ
- Price visible
- Before intake
The verdict
Direct Meds prints its price before the medical intake, which is the entry condition rather than the finish, and gives some of it back on the rest of the question — what the advertised figure is attached to, or who fills the prescription. It lands at 28 of 35.
The number beside Direct Meds's name answers one question — can you find out what this costs before you hand over your medical history? — and it is dominated by that. A program is credited for naming the pharmacies that compound its medicine and for publishing a certification credential, and docked when the advertised rate needs a commitment, when a second fee sits outside it, when the seller's own terms say the published figure is not what it will charge, and when the FDA has a warning letter on file. What the price turns out to be is not an input at all, which is why a cheaper program can sit below a dearer one here.
Who it is for, and who it is not
A good fit if
You want to compare before you hand anything over
Direct Meds publishes what it charges before the medical intake, so you can weigh it against anything else on this page without first giving a company your health history.
You want to know who makes the medicine
It names CraftedRx, ChemistryRx publicly. A compounded medicine is only as good as the pharmacy that made it, and a company willing to name one is a company you can go and check.
Look elsewhere if
You want a seller with nothing on the public record
The agency's public record has an entry naming this company. What it is, who exactly it names and when it was issued are set out in their own section on this page, where we link the agency rather than summarizing it. It has changed neither where this program sits here nor whether we are paid for a click to it — and you should know both of those at once, which is why it is on the page rather than left out.
What it actually costs
Both figures below are reproduced exactly as we recorded them, with every condition attached. They are long on purpose: a monthly rate quoted without the term that buys it, the cadence it is billed on, or the dose it applies to is the single most common way a price on a page like this turns out to be untrue.
From $249/mo (compounded oral)
From $299/mo (compounded oral)
All US states except Mississippi and Louisiana, per its own FAQ
Direct Meds pays us a commission if you start care through this link — as does every company with a review here, which is what decides who gets one, so this is not a survey of the market. See our disclosure, and weigh the trade-offs above against the evidence rather than taking our word for it. Direct Meds sells a prescription medicine, not a probiotic; this site's ranked shelf is the metabolic probiotic ranking, and a supplement is a different decision from a drug.
The pharmacy behind the medicine
It names its pharmacy. Direct Meds discloses CraftedRx, ChemistryRx as its compounding partners. That matters more here than the price does: a compounded medicine is only as good as the pharmacy that made it, and a company willing to name one is a company you can go and check.
A compounded drug is mixed to order by a pharmacy rather than manufactured and released as a finished product, so the FDA has not reviewed the specific preparation you are prescribed for safety, effectiveness or quality. That is true of every compounded program on this page, including the ones that score highest, and it is the most important sentence on it.
The honest read
What it does well
- Semaglutide and tirzepatide available in both injection and sublingual formats
- All-inclusive pricing covers medication, consultations, supplies, and 1–2 day temperature-controlled shipping
- LegitScript Certified
- Named 503A pharmacy partners: CraftedRx (MO) and ChemistryRx (PA)
What to check first
- BBB rating 1.12/5 across 226 reviews citing a hidden 3-month commitment (charges of $940+ when buyers expected 1 month)
- Wide rating gap: Trustpilot 4.6/5 vs BBB 1.12/5 — points to review-solicitation bias or unresolved complaints
- Not available in Mississippi, Louisiana, or California
- Compounded medications are not FDA-approved finished products
What is on the public record
FDA warning letter
FDA issued a warning letter to directmeds.com, Inc. dba DirectMeds in September 2025. It is on the public record in FDA's warning-letter database.
We link the agency's own index rather than summarize what the letter says. It changes neither where this program sits in our ranking nor whether we are paid for a click to it, and you should know both of those at once.
How it compares
Direct Meds sits at 28 of 35 on this page. Every prescription GLP-1 program this site links out to is scored on the same question: can you see the price before you hand over your health history? The full list is on the prescription GLP-1 review index.
Because Direct Meds prints a figure before the intake rather than after it, it is also a ranked row on our GLP-1 telehealth ranking, our compounded semaglutide ranking and our compounded tirzepatide ranking. Each is this same question narrowed to the programs that answer it, with every figure printed as we recorded it and its conditions attached rather than trimmed to fit a column.
- Strut Health review
From $99/mo (compounded oral)
- Collective review
$59/mo for compounded semaglutide at any dose, plus a required $199 ANNUAL membership. Billed once a year, not monthly — a first year comes to $907Show the full pricing note
- MadeMed review
$239/mo on the shortest plan it sells (compounded weekly injection its page describes as enhanced with L-carnitine, billed $717 up front every 3 months; no month-to-month rung exists — $199/mo needs 6 months at $1,194 up front, and a vial ships every 2 months against a 3-month billing cycle)Show the full pricing note
- WellMedr review
$99 per cycle month-to-month — but a plan it calls "1 Month Supply" bills every 21 DAYS, which is 17.38 charges a year and $143/calendar month, not $99; the $59/mo on its card is the 12-month rung ($708 every 350 days)Show the full pricing note
- Eden review
$99/mo all-inclusive on the page our link opens (compounded weekly injection, flat at every dose, "no membership fees" and a lifetime price guarantee — while eden.health's own weight-loss page sells the same molecule at $99 medication-only plus a mandatory $99/mo membership, $198/mo all-in)Show the full pricing note
Read this before you start
Checked on Direct Meds's own site on . Prices change — confirm on Direct Meds's own site before you commit. This page is informational and not medical advice: a GLP-1 is a prescription drug, and whether one suits you is a decision for a licensed clinician who knows your history. How we choose what appears here, and what we are paid for, is set out in our editorial policy.